Best Weakness Champions in MCOC

34 champions can inflict Weakness, sorted by their place on the combined tier list so the strongest come first. Updated November 2026.

S+ Tier 4

  1. 8Human TorchS+100
  2. 16OkoyeS+100
  3. 24YonduS+100
  4. 30JuggernautS+96

S Tier 1

  1. 55She-Hulk (Deathless)S88

A Tier 6

  1. 77MagnetoA82
  2. 97She-HulkA78
  3. 101Werewolf By NightA78
  4. 105Spider-Man (Symbiote)A76
  5. 111TitaniaA74
  6. 116Symbiote SupremeA72

B Tier 5

  1. 128KindredB68
  2. 136VoidB68
  3. 162Blue MarvelB60
  4. 166Mister FantasticB60
  5. 168PatriotB60

C Tier 9

  1. 171ApocalypseC59
  2. 178Joe FixitC59
  3. 182Abomination (Immortal)C58
  4. 187Hulk (Immortal)C56
  5. 214Captain America (Infinity War)C50
  6. 220Spider-ManC50
  7. 225RonanC47
  8. 233Scarlet Witch (Classic)C46
  9. 236ThingC46

D Tier 5

  1. 247Jessica JonesD41
  2. 260M.O.D.O.K.D36
  3. 261MorbiusD36
  4. 267Spider-Man (Miles Morales)D34
  5. 278WaspD32

F Tier 4

  1. 294Civil WarriorF26
  2. 296Hulk (Ragnarok)F26
  3. 326Psycho-ManF20
  4. 335Green GoblinF18

Other debuffs: Armor Break · Armor Shattered · Bleed · Coldsnap · Concussion · Degeneration · Delirium · Disorient · Enervate · Exhaustion · Falter · Fate Seal · Fatigue · Frostbite · Heal Block · Incinerate · Neutralize · Nova Flame · Nullify · Petrify · Plasma · Poison · Power Burn · Power Drain · Power Lock · Power Sting · Rupture · Sabotage · Shock · Sleep · Slow · Stagger · Stun · Taunt