3 champions can inflict Delirium, sorted by their place on the combined tier list so the strongest come first. Updated November 2026. Fighting a Delirium champion? See who is immune to Delirium.
Other debuffs: Armor Break · Armor Shattered · Bleed · Coldsnap · Concussion · Degeneration · Disorient · Enervate · Exhaustion · Falter · Fate Seal · Fatigue · Frostbite · Heal Block · Incinerate · Neutralize · Nova Flame · Nullify · Petrify · Plasma · Poison · Power Burn · Power Drain · Power Lock · Power Sting · Rupture · Sabotage · Shock · Sleep · Slow · Stagger · Stun · Taunt · Weakness
