Best Enervate Champions in MCOC

8 champions can inflict Enervate, sorted by their place on the combined tier list so the strongest come first. Updated November 2026.

A Tier 1

  1. 80Spider-Man (Stealth Suit)A82

C Tier 2

  1. 182Abomination (Immortal)C58
  2. 230Mister NegativeC46

D Tier 2

  1. 249Spider-GwenD41
  2. 286PsylockeD30

F Tier 3

  1. 296Hulk (Ragnarok)F26
  2. 304GwenpoolF24
  3. 307AbominationF20

Other debuffs: Armor Break · Armor Shattered · Bleed · Coldsnap · Concussion · Degeneration · Delirium · Disorient · Exhaustion · Falter · Fate Seal · Fatigue · Frostbite · Heal Block · Incinerate · Neutralize · Nova Flame · Nullify · Petrify · Plasma · Poison · Power Burn · Power Drain · Power Lock · Power Sting · Rupture · Sabotage · Shock · Sleep · Slow · Stagger · Stun · Taunt · Weakness