Best Exhaustion Champions in MCOC

12 champions can inflict Exhaustion, sorted by their place on the combined tier list so the strongest come first. Updated November 2026.

S+ Tier 1

  1. 9Jean GreyS+100

S Tier 1

  1. 34Captain BritainS95

A Tier 3

  1. 76Luke CageA82
  2. 97She-HulkA78
  3. 111TitaniaA74

B Tier 2

  1. 154Spider-Man 2099B64
  2. 169SentryB60

C Tier 3

  1. 177High EvolutionaryC59
  2. 217Invisible WomanC50
  3. 230Mister NegativeC46

D Tier 2

  1. 247Jessica JonesD41
  2. 260M.O.D.O.K.D36

Other debuffs: Armor Break · Armor Shattered · Bleed · Coldsnap · Concussion · Degeneration · Delirium · Disorient · Enervate · Falter · Fate Seal · Fatigue · Frostbite · Heal Block · Incinerate · Neutralize · Nova Flame · Nullify · Petrify · Plasma · Poison · Power Burn · Power Drain · Power Lock · Power Sting · Rupture · Sabotage · Shock · Sleep · Slow · Stagger · Stun · Taunt · Weakness