Best Nullify Champions in MCOC

46 champions can inflict Nullify, sorted by their place on the combined tier list so the strongest come first. Updated November 2026. Fighting a Nullify champion? See who is immune to Nullify.

S+ Tier 5

  1. 6Doctor StrangeS+100
  2. 12KushalaS+100
  3. 13Madelyne PryorS+100
  4. 19Spider-Man (Pavitr Prabhakar)S+100
  5. 30JuggernautS+96

S Tier 4

  1. 46TigraS92
  2. 47VenomS92
  3. 51MojoS91
  4. 58Doctor DoomS86

A Tier 5

  1. 79ShathraA82
  2. 93MagikA78
  3. 95PurgatoryA78
  4. 101Werewolf By NightA78
  5. 116Symbiote SupremeA72

B Tier 6

  1. 122Blade (Stellar Forge)B68
  2. 138White TigerB68
  3. 141Black Widow (Claire Voyant)B64
  4. 146LongshotB64
  5. 160WongB61
  6. 163DiabloB60

C Tier 12

  1. 197MordoC54
  2. 201Thor (Jane Foster)C54
  3. 210Spider-Man (Supreme)C51
  4. 214Captain America (Infinity War)C50
  5. 216Doctor VoodooC50
  6. 218Man-ThingC50
  7. 221WiccanC50
  8. 223Scarlet WitchC49
  9. 226EnchantressC46
  10. 233Scarlet Witch (Classic)C46
  11. 234Sorcerer SupremeC46
  12. 236ThingC46

D Tier 7

  1. 240DraculaD42
  2. 249Spider-GwenD41
  3. 252RogueD40
  4. 256Guillotine (Deathless)D38
  5. 259IsophyneD36
  6. 271Ebony MawD32
  7. 284Ms. Marvel (Kamala Khan)D30

F Tier 7

  1. 295DormammuF26
  2. 297MorningstarF26
  3. 305MangogF24
  4. 311Captain America (WWII)F20
  5. 319Iron FistF20
  6. 320Iron Fist (Immortal)F20
  7. 323LokiF20

Other debuffs: Armor Break · Armor Shattered · Bleed · Coldsnap · Concussion · Degeneration · Delirium · Disorient · Enervate · Exhaustion · Falter · Fate Seal · Fatigue · Frostbite · Heal Block · Incinerate · Neutralize · Nova Flame · Petrify · Plasma · Poison · Power Burn · Power Drain · Power Lock · Power Sting · Rupture · Sabotage · Shock · Sleep · Slow · Stagger · Stun · Taunt · Weakness