10 champions are immune to Heal Block, sorted by their place on the tier list so the best options come first. 3 of them are only immune under a condition, such as a mode or an ability being active. Updated November 2026.
Other immunities: Armor Break · Armor Shattered · Bleed · Buff Immunity · Coldsnap · Delirium · Fate Seal · Frostbite · Incinerate · Inverted Controls · Nullify · Poison · Power Burn · Power Drain · Power Lock · Power Steal · Regen Rate Mod · Rupture · Shock · Stagger